What is another word for

adversity

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adversity as in a state of misfortune or affliction

"debt-ridden farmers struggling with adversity"
"a life of hardship"

Synonyms

hardshipa state of misfortune or affliction; something hard to endure; something that causes or entails suffering
hard knocksa state of misfortune or affliction

adversity as in a stroke of ill fortune

"a calamitous event"
"a period marked by adversities"